BDBM50467517 CHEMBL4286877

SMILES: Cc1ccc(NC(=O)c2coc3ccc(\C=C\C(O)=O)cc3c2=O)cc1C

InChI Key: InChIKey=XHXQSDWCRTXPQX-VMPITWQZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50467517 (CHEMBL4286877) Show SMILES Cc1ccc(NC(=O)c2coc3ccc(\C=C\C(O)=O)cc3c2=O)cc1C Show InChI InChI=1S/C21H17NO5/c1-12-3-6-15(9-13(12)2)22-21(26)17-11-27-18-7-4-14(5-8-19(23)24)10-16(18)20(17)25/h3-11H,1-2H3,(H,22,26)(H,23,24)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decrease in H2O2...				Eur J Med Chem 158: 781-800 (2018) Article DOI: 10.1016/j.ejmech.2018.07.056 BindingDB Entry DOI: 10.7270/Q2F192DM
					More data for this Ligand-Target Pair