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SMILES: OC(=O)\C=C\c1ccc2oc(cc(=O)c2c1)C(=O)Nc1ccccc1

InChI Key: InChIKey=ZXLVCFXOIDADKY-VQHVLOKHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467523   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Homo sapiens (Human))		BDBM50467523
PNG
(CHEMBL4279249)
Show SMILES OC(=O)\C=C\c1ccc2oc(cc(=O)c2c1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H13NO5/c21-15-11-17(19(24)20-13-4-2-1-3-5-13)25-16-8-6-12(10-14(15)16)7-9-18(22)23/h1-11H,(H,20,24)(H,22,23)/b9-7+
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PC cid
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Article
PubMed
n/an/a 5.99E+3n/an/an/an/an/an/a



University of Porto

Curated by ChEMBL


Assay Description
Inhibition of human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured after 5 mins by El...

Eur J Med Chem 158: 781-800 (2018)


Article DOI: 10.1016/j.ejmech.2018.07.056
BindingDB Entry DOI: 10.7270/Q2F192DM
More data for this
Ligand-Target Pair