BDBM50467840 CHEMBL4286329

SMILES: Cc1cc(O)c(cc1Cc1ccc(CCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key: InChIKey=AUGARWHQIUJYHM-RXFVIIJJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50467840 (CHEMBL4286329) Show SMILES Cc1cc(O)c(cc1Cc1ccc(CCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C27H38N2O8/c1-15-10-20(32)19(25-24(35)23(34)22(33)21(13-30)37-25)12-18(15)11-17-6-4-16(5-7-17)8-9-28-26(36)29-27(2,3)14-31/h4-7,10,12,21-25,30-35H,8-9,11,13-14H2,1-3H3,(H2,28,29,36)/t21-,22-,23+,24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...				Bioorg Med Chem Lett 28: 3534-3539 (2018) Article DOI: 10.1016/j.bmcl.2018.09.035 BindingDB Entry DOI: 10.7270/Q2V40XWK
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50467840 (CHEMBL4286329) Show SMILES Cc1cc(O)c(cc1Cc1ccc(CCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C27H38N2O8/c1-15-10-20(32)19(25-24(35)23(34)22(33)21(13-30)37-25)12-18(15)11-17-6-4-16(5-7-17)8-9-28-26(36)29-27(2,3)14-31/h4-7,10,12,21-25,30-35H,8-9,11,13-14H2,1-3H3,(H2,28,29,36)/t21-,22-,23+,24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...				Bioorg Med Chem Lett 28: 3534-3539 (2018) Article DOI: 10.1016/j.bmcl.2018.09.035 BindingDB Entry DOI: 10.7270/Q2V40XWK
					More data for this Ligand-Target Pair