BDBM50467842 CHEMBL4289746

SMILES: Cc1cc(O)c(cc1Cc1ccc(CCCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key: InChIKey=FJOITVVEXYTSAM-RTJMFUJLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50467842 (CHEMBL4289746) Show SMILES Cc1cc(O)c(cc1Cc1ccc(CCCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H40N2O8/c1-16-11-21(33)20(26-25(36)24(35)23(34)22(14-31)38-26)13-19(16)12-18-8-6-17(7-9-18)5-4-10-29-27(37)30-28(2,3)15-32/h6-9,11,13,22-26,31-36H,4-5,10,12,14-15H2,1-3H3,(H2,29,30,37)/t22-,23-,24+,25-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...				Bioorg Med Chem Lett 28: 3534-3539 (2018) Article DOI: 10.1016/j.bmcl.2018.09.035 BindingDB Entry DOI: 10.7270/Q2V40XWK
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50467842 (CHEMBL4289746) Show SMILES Cc1cc(O)c(cc1Cc1ccc(CCCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C28H40N2O8/c1-16-11-21(33)20(26-25(36)24(35)23(34)22(14-31)38-26)13-19(16)12-18-8-6-17(7-9-18)5-4-10-29-27(37)30-28(2,3)15-32/h6-9,11,13,22-26,31-36H,4-5,10,12,14-15H2,1-3H3,(H2,29,30,37)/t22-,23-,24+,25-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...				Bioorg Med Chem Lett 28: 3534-3539 (2018) Article DOI: 10.1016/j.bmcl.2018.09.035 BindingDB Entry DOI: 10.7270/Q2V40XWK
					More data for this Ligand-Target Pair