BDBM50468209 CHEMBL4285692

SMILES: CC1(C)Cc2c(c(nn2C1)-c1ccccn1)-c1ccncc1

InChI Key: InChIKey=FZHWDOVVRCKMQN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468209 (CHEMBL4285692) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccn1)-c1ccncc1 Show InChI InChI=1S/C18H18N4/c1-18(2)11-15-16(13-6-9-19-10-7-13)17(21-22(15)12-18)14-5-3-4-8-20-14/h3-10H,11-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
CDK2/CycE (Homo sapiens (Human))	BDBM50468209 (CHEMBL4285692) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccn1)-c1ccncc1 Show InChI InChI=1S/C18H18N4/c1-18(2)11-15-16(13-6-9-19-10-7-13)17(21-22(15)12-18)14-5-3-4-8-20-14/h3-10H,11-12H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468209 (CHEMBL4285692) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccn1)-c1ccncc1 Show InChI InChI=1S/C18H18N4/c1-18(2)11-15-16(13-6-9-19-10-7-13)17(21-22(15)12-18)14-5-3-4-8-20-14/h3-10H,11-12H2,1-2H3	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair