BDBM50469549 CHEMBL4092311

SMILES: C[C@@H](N)[C@H](NC(=O)c1ccc(OC(C)(C)C)cc1)C(=O)NO

InChI Key: InChIKey=BUPYKKSBGNHXMV-SKDRFNHKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50469549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC) (Pseudomonas aeruginosa)	BDBM50469549 (CHEMBL4092311) Show SMILES C[C@@H](N)[C@H](NC(=O)c1ccc(OC(C)(C)C)cc1)C(=O)NO |r| Show InChI InChI=1S/C15H23N3O4/c1-9(16)12(14(20)18-21)17-13(19)10-5-7-11(8-6-10)22-15(2,3)4/h5-9,12,21H,16H2,1-4H3,(H,17,19)(H,18,20)/t9-,12+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0830	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa LpxC using UDP-3-O-(R-hydroxydecanoyl)-N-acetylglucosamine as substrate preincubated for 30 mins followed by sub...				J Med Chem 60: 5002-5014 (2017) Article DOI: 10.1021/acs.jmedchem.7b00377 BindingDB Entry DOI: 10.7270/Q2FN18MZ
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