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SMILES: Oc1cc(nc2ccc(cc12)N1CCCC1)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=IXOPCLABJYZIEL-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470028   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)		BDBM50470028
PNG
(CHEMBL114849)
Show SMILES Oc1cc(nc2ccc(cc12)N1CCCC1)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C20H17F3N2O2/c21-20(22,23)27-15-5-3-4-13(10-15)18-12-19(26)16-11-14(6-7-17(16)24-18)25-8-1-2-9-25/h3-7,10-12H,1-2,8-9H2,(H,24,26)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 720n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of bovine tubulin polymerization

J Med Chem 37: 3400-7 (1994)


Article DOI: 10.1021/jm00046a025
BindingDB Entry DOI: 10.7270/Q2HQ42MX
More data for this
Ligand-Target Pair