null

SMILES: CCNC(=O)[C@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCc1ccc(F)cc1

InChI Key: InChIKey=RCAGVLFSQAOJJI-XQLZYTMYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50470099 (CHEMBL2371295) Show SMILES CCNC(=O)[C@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCc1ccc(F)cc1 |wU:55.60,12.20,wD:43.54,31.41,23.28,5.4,61.64,(27.36,-6,;27.38,-7.53,;26.06,-8.31,;24.72,-7.54,;23.42,-8.31,;24.69,-6.05,;25.9,-5.16,;25.38,-3.71,;23.85,-3.73,;23.43,-5.16,;22.1,-5.92,;22.08,-7.44,;20.76,-5.16,;20.78,-3.61,;22.11,-2.84,;22.14,-1.32,;23.47,-.56,;23.49,.99,;24.82,1.74,;22.15,1.76,;19.44,-5.9,;18.11,-5.13,;18.12,-3.58,;16.77,-5.89,;16.76,-7.43,;18.09,-8.22,;19.41,-7.44,;18.06,-9.75,;15.44,-5.12,;14.1,-5.87,;14.1,-7.4,;12.78,-5.09,;12.88,-3.57,;13.64,-2.23,;12.85,-.9,;13.59,.45,;15.15,.47,;15.9,1.82,;15.94,-.87,;15.19,-2.2,;11.46,-5.86,;10.11,-5.06,;10.11,-3.54,;8.78,-5.83,;8.78,-7.37,;10.1,-8.15,;10.08,-9.7,;11.42,-10.47,;12.75,-9.72,;14.07,-10.47,;12.77,-8.17,;11.43,-7.38,;7.46,-5.05,;6.12,-5.8,;6.11,-7.35,;4.8,-5.03,;4.8,-3.51,;6.12,-2.75,;3.45,-5.79,;2.13,-5.02,;2.16,-3.49,;.78,-5.77,;.78,-7.31,;2.1,-8.09,;3.52,-7.47,;4.55,-8.62,;3.76,-9.95,;4.23,-11.42,;3.2,-12.55,;1.68,-12.23,;1.22,-10.76,;2.26,-9.63,;-.54,-5,;-1.87,-5.76,;-1.79,-7.27,;-3.25,-5.08,;-4.65,-6.09,;-6.21,-5.38,;-7.61,-6.4,;-9.17,-5.71,;-9.35,-4,;-10.9,-3.22,;-7.97,-2.97,;-6.39,-3.68,)| Show InChI InChI=1S/C60H76ClFN12O10/c1-4-65-58(83)51-12-8-28-74(51)59(84)45(11-7-27-66-60(63)64)69-53(78)46(29-35(2)3)70-54(79)47(30-37-13-20-40(61)21-14-37)71-55(80)48(31-38-17-24-42(76)25-18-38)72-57(82)50(34-75)73-56(81)49(32-39-33-67-44-10-6-5-9-43(39)44)68-52(77)26-19-36-15-22-41(62)23-16-36/h5-6,9-10,13-18,20-25,33,35,45-51,67,75-76H,4,7-8,11-12,19,26-32,34H2,1-3H3,(H,65,83)(H,68,77)(H,69,78)(H,70,79)(H,71,80)(H,72,82)(H,73,81)(H4,63,64,66)/t45-,46-,47+,48-,49-,50-,51+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TAP Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of the in vitro binding of [125I]-labeled leuprolide to the rat pituitary luteinizing hormone releasing hormone (LHRH) receptor.				J Med Chem 37: 701-5 (1994) Article DOI: 10.1021/jm00031a021 BindingDB Entry DOI: 10.7270/Q2MG7S7B
					More data for this Ligand-Target Pair