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BDBM50470149 CHEMBL46981

SMILES: Clc1ccc(OC\C=C\c2ccccc2)c(c1)C(=O)c1ccccc1

InChI Key: InChIKey=FRPLYSXYNYZSMO-JXMROGBWSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470149   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50470149
PNG
(CHEMBL46981)
Show SMILES Clc1ccc(OC\C=C\c2ccccc2)c(c1)C(=O)c1ccccc1
Show InChI InChI=1S/C22H17ClO2/c23-19-13-14-21(25-15-7-10-17-8-3-1-4-9-17)20(16-19)22(24)18-11-5-2-6-12-18/h1-14,16H,15H2/b10-7+
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.86E+5n/an/an/an/an/an/a



Glaxo Research and Development Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase

J Med Chem 38: 1657-65 (1995)


Article DOI: 10.1021/jm00010a010
BindingDB Entry DOI: 10.7270/Q27947DP
More data for this
Ligand-Target Pair