BindingDB logo
myBDB logout

null

SMILES: Clc1ccc(OCC(=O)Nc2ccccc2)c(c1)C(=O)c1cccnc1

InChI Key: InChIKey=KNNDZKBPMGQMMG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470151   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50470151
PNG
(CHEMBL297010)
Show SMILES Clc1ccc(OCC(=O)Nc2ccccc2)c(c1)C(=O)c1cccnc1
Show InChI InChI=1S/C20H15ClN2O3/c21-15-8-9-18(17(11-15)20(25)14-5-4-10-22-12-14)26-13-19(24)23-16-6-2-1-3-7-16/h1-12H,13H2,(H,23,24)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 436n/an/an/an/an/an/a



Glaxo Research and Development Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase

J Med Chem 38: 1657-65 (1995)


Article DOI: 10.1021/jm00010a010
BindingDB Entry DOI: 10.7270/Q27947DP
More data for this
Ligand-Target Pair