BDBM50470187 CHEMBL428882
SMILES: COc1ccc2ccc(OC)c(CCNC(C)=O)c2c1
InChI Key: InChIKey=GURZWDBOLSYLPG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Melatonin receptor type 1C (Gallus gallus) | BDBM50470187![]() (CHEMBL428882) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470187![]() (CHEMBL428882) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Inhibition of 2-[125I]- iodomelatonin from chicken brain melatonin receptors | J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470187![]() (CHEMBL428882) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470187![]() (CHEMBL428882) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.0370 | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin | J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM | |||||||||||
More data for this Ligand-Target Pair |