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BDBM50470209 CHEMBL75921

SMILES: CCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(nc(SC)c2C(O)=O)C2CC2)cc1

InChI Key: InChIKey=DBTXMTFNEQQKJK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470209   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II receptor (AT-1) type-1


(RAT)		BDBM50470209
PNG
(CHEMBL75921)
Show SMILES CCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(nc(SC)c2C(O)=O)C2CC2)cc1
Show InChI InChI=1S/C25H28N4O5S2/c1-3-14-26-25(32)28-36(33,34)20-7-5-4-6-19(20)17-10-8-16(9-11-17)15-29-21(24(30)31)23(35-2)27-22(29)18-12-13-18/h4-11,18H,3,12-15H2,1-2H3,(H,30,31)(H2,26,28,32)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.70n/an/an/an/an/an/a



Hoechst Roussel PGU Cardiovascular Agents

Curated by ChEMBL


Assay Description
Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane

J Med Chem 38: 2357-77 (1995)


Article DOI: 10.1021/jm00013a013
BindingDB Entry DOI: 10.7270/Q2KK9FH8
More data for this
Ligand-Target Pair