BindingDB logo
myBDB logout

null

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-n1ccc2cc(ccc12)-[#6](\[#6])=[#6]\[#6](=O)-[#7]-c1ccccc1-[#8]-[#6]-[#6]-[#6]-[#6](-[#8])=O

InChI Key: InChIKey=XSKGOISZZYTHNB-LVZFUZTISA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470265   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2


(Rattus norvegicus)		BDBM50470265
PNG
(CHEMBL97248)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1ccc2cc(ccc12)-[#6](\[#6])=[#6]\[#6](=O)-[#7]-c1ccccc1-[#8]-[#6]-[#6]-[#6]-[#6](-[#8])=O
Show InChI InChI=1S/C27H30N2O4/c1-19(2)12-14-29-15-13-22-18-21(10-11-24(22)29)20(3)17-26(30)28-23-7-4-5-8-25(23)33-16-6-9-27(31)32/h4-5,7-8,10-13,15,17-18H,6,9,14,16H2,1-3H3,(H,28,30)(H,31,32)/b20-17+
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats

J Med Chem 38: 2887-92 (1995)


Article DOI: 10.1021/jm00015a011
BindingDB Entry DOI: 10.7270/Q2B27Z0N
More data for this
Ligand-Target Pair