Found 5 hits for monomerid = 50470454 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Monoglyceride lipase
(Homo sapiens (Human)) | BDBM50470454
![PNG](/data/jpeg/tenK5047/BindingDB_50470454.png) (CHEMBL4282040)Show SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO3/c20-16-6-4-13(5-7-16)18(23)14-8-10-21(11-9-14)19(24)15-2-1-3-17(22)12-15/h1-7,12,14,22H,8-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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PC cid PC sid UniChem
| | 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Monoglyceride lipase
(Homo sapiens (Human)) | BDBM50470454
![PNG](/data/jpeg/tenK5047/BindingDB_50470454.png) (CHEMBL4282040)Show SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO3/c20-16-6-4-13(5-7-16)18(23)14-8-10-21(11-9-14)19(24)15-2-1-3-17(22)12-15/h1-7,12,14,22H,8-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pisa
Curated by ChEMBL
| Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins |
J Med Chem 62: 1932-1958 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01483 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50470454
![PNG](/data/jpeg/tenK5047/BindingDB_50470454.png) (CHEMBL4282040)Show SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO3/c20-16-6-4-13(5-7-16)18(23)14-8-10-21(11-9-14)19(24)15-2-1-3-17(22)12-15/h1-7,12,14,22H,8-11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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PC cid PC sid UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Monoglyceride lipase
(Homo sapiens (Human)) | BDBM50470454
![PNG](/data/jpeg/tenK5047/BindingDB_50470454.png) (CHEMBL4282040)Show SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO3/c20-16-6-4-13(5-7-16)18(23)14-8-10-21(11-9-14)19(24)15-2-1-3-17(22)12-15/h1-7,12,14,22H,8-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pisa
Curated by ChEMBL
| Assay Description Inhibition of recombinant human C-terminal His-tagged MAGL expressed in Escherichia coli using 4-NPA as substrate measured after 30 mins |
Eur J Med Chem 157: 817-836 (2018)
Article DOI: 10.1016/j.ejmech.2018.08.038 BindingDB Entry DOI: 10.7270/Q2MS3WG9 |
More data for this Ligand-Target Pair | |
Monoglyceride lipase
(Homo sapiens (Human)) | BDBM50470454
![PNG](/data/jpeg/tenK5047/BindingDB_50470454.png) (CHEMBL4282040)Show SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO3/c20-16-6-4-13(5-7-16)18(23)14-8-10-21(11-9-14)19(24)15-2-1-3-17(22)12-15/h1-7,12,14,22H,8-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
PC cid PC sid UniChem
| | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |