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SMILES: COC(=O)CC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1

InChI Key: InChIKey=USMVLJXQPRGGDK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470742   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50470742
PNG
(CHEMBL35486)
Show SMILES COC(=O)CC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1
Show InChI InChI=1S/C20H27NO5/c1-24-17-8-7-14(11-18(17)26-16-5-3-4-6-16)15-9-10-21(13-15)19(22)12-20(23)25-2/h7-8,11,15-16H,3-6,9-10,12-13H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 589n/an/an/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme

J Med Chem 38: 1505-10 (1995)


Article DOI: 10.1021/jm00009a011
BindingDB Entry DOI: 10.7270/Q2833VRG
More data for this
Ligand-Target Pair