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SMILES: COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)Nc1ccccc1

InChI Key: InChIKey=DNSOSBOERXEYEJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470746   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50470746
PNG
(CHEMBL37386)
Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C23H28N2O3/c1-27-21-12-11-17(15-22(21)28-20-9-5-6-10-20)18-13-14-25(16-18)23(26)24-19-7-3-2-4-8-19/h2-4,7-8,11-12,15,18,20H,5-6,9-10,13-14,16H2,1H3,(H,24,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 427n/an/an/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme

J Med Chem 38: 1505-10 (1995)


Article DOI: 10.1021/jm00009a011
BindingDB Entry DOI: 10.7270/Q2833VRG
More data for this
Ligand-Target Pair