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SMILES: COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)C#CC

InChI Key: InChIKey=ZBYOJSFWWJDESD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470747   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50470747
PNG
(CHEMBL38219)
Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)C#CC
Show InChI InChI=1S/C20H25NO3/c1-3-6-20(22)21-12-11-16(14-21)15-9-10-18(23-2)19(13-15)24-17-7-4-5-8-17/h9-10,13,16-17H,4-5,7-8,11-12,14H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 195n/an/an/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme

J Med Chem 38: 1505-10 (1995)


Article DOI: 10.1021/jm00009a011
BindingDB Entry DOI: 10.7270/Q2833VRG
More data for this
Ligand-Target Pair