BindingDB logo
myBDB logout

null

SMILES: COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)N(C)C

InChI Key: InChIKey=AAOFUKNAVQIXDY-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470749   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50470749
PNG
(CHEMBL34846)
Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)N(C)C
Show InChI InChI=1S/C19H28N2O3/c1-20(2)19(22)21-11-10-15(13-21)14-8-9-17(23-3)18(12-14)24-16-6-4-5-7-16/h8-9,12,15-16H,4-7,10-11,13H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 145n/an/an/an/an/an/an/an/a



Glaxo Research Institute

Curated by ChEMBL


Assay Description
Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme

J Med Chem 38: 1505-10 (1995)


Article DOI: 10.1021/jm00009a011
BindingDB Entry DOI: 10.7270/Q2833VRG
More data for this
Ligand-Target Pair