null

SMILES: CCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12

InChI Key: InChIKey=ICLUJHGSWBKLKJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50471432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471432 (CHEMBL118314) Show SMILES CCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12 Show InChI InChI=1S/C20H19NO3/c1-2-3-13-8-12-9-14(23)4-6-16(12)20-18(11-22)17-7-5-15(24)10-19(17)21(13)20/h4-7,9-11,13,23-24H,2-3,8H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization using isolated calf brain				J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471432 (CHEMBL118314) Show SMILES CCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12 Show InChI InChI=1S/C20H19NO3/c1-2-3-13-8-12-9-14(23)4-6-16(12)20-18(11-22)17-7-5-15(24)10-19(17)21(13)20/h4-7,9-11,13,23-24H,2-3,8H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of Tubulin polymerization by a 40 uM solution of compound; compound showed inhibition >50% at 40 uM				J Med Chem 41: 4965-72 (1998) Article DOI: 10.1021/jm980228l BindingDB Entry DOI: 10.7270/Q2NV9N0D
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471432 (CHEMBL118314) Show SMILES CCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12 Show InChI InChI=1S/C20H19NO3/c1-2-3-13-8-12-9-14(23)4-6-16(12)20-18(11-22)17-7-5-15(24)10-19(17)21(13)20/h4-7,9-11,13,23-24H,2-3,8H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization using isolated calf brain				J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH
					More data for this Ligand-Target Pair