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SMILES: COc1ccc(\C=C(\C(N)=O)c2cc(OC)c(OC)c(OC)c2)cc1N

InChI Key: InChIKey=IOUONEQKDUSPAJ-NTUHNPAUSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50471733   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)		BDBM50471733
PNG
(CHEMBL319183)
Show SMILES COc1ccc(\C=C(\C(N)=O)c2cc(OC)c(OC)c(OC)c2)cc1N
Show InChI InChI=1S/C19H22N2O5/c1-23-15-6-5-11(8-14(15)20)7-13(19(21)22)12-9-16(24-2)18(26-4)17(10-12)25-3/h5-10H,20H2,1-4H3,(H2,21,22)/b13-7+
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Ajinomoto Company Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization

J Med Chem 41: 3022-32 (1998)


Article DOI: 10.1021/jm980101w
BindingDB Entry DOI: 10.7270/Q2QV3Q85
More data for this
Ligand-Target Pair