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SMILES: COc1ccc(cc1)C(=C/c1ccc(OC)c(N)c1)\C#N

InChI Key: InChIKey=BSLJQCZQUKBZDO-ZROIWOOFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50471749   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)		BDBM50471749
PNG
(CHEMBL316750)
Show SMILES COc1ccc(cc1)C(=C/c1ccc(OC)c(N)c1)\C#N
Show InChI InChI=1S/C17H16N2O2/c1-20-15-6-4-13(5-7-15)14(11-18)9-12-3-8-17(21-2)16(19)10-12/h3-10H,19H2,1-2H3/b14-9-
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Ajinomoto Company Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization

J Med Chem 41: 3022-32 (1998)


Article DOI: 10.1021/jm980101w
BindingDB Entry DOI: 10.7270/Q2QV3Q85
More data for this
Ligand-Target Pair