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SMILES: [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S(=O)(=O)[#6]-[#6]C21[#8]-[#6]-[#6]-[#8]1

InChI Key: InChIKey=CIOWDLVIPMGCFN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50471793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 3


(Oryctolagus cuniculus)		BDBM50471793
PNG
(CHEMBL121787)
Show SMILES [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S(=O)(=O)[#6]-[#6]C21[#8]-[#6]-[#6]-[#8]1
Show InChI InChI=1S/C14H17N3O5S/c1-8-6-10-11(7-9(8)12(18)17-13(15)16)23(19,20)5-2-14(10)21-3-4-22-14/h6-7H,2-5H2,1H3,(H4,15,16,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes

J Med Chem 41: 3736-47 (1998)


Article DOI: 10.1021/jm981031w
BindingDB Entry DOI: 10.7270/Q2BK1G33
More data for this
Ligand-Target Pair