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SMILES: Cc1nc(CO)nc2n(Cc3ccc(cc3)-c3ccccc3-c3nn[nH]n3)c(=O)cc(O)c12

InChI Key: InChIKey=AYEBUIVINDPNBD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50471877   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor A/B


(RAT)		BDBM50471877
PNG
(CHEMBL135574)
Show SMILES Cc1nc(CO)nc2n(Cc3ccc(cc3)-c3ccccc3-c3nn[nH]n3)c(=O)cc(O)c12
Show InChI InChI=1S/C23H19N7O3/c1-13-21-18(32)10-20(33)30(23(21)25-19(12-31)24-13)11-14-6-8-15(9-7-14)16-4-2-3-5-17(16)22-26-28-29-27-22/h2-10,31-32H,11-12H2,1H3,(H,26,27,28,29)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.410n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.

J Med Chem 41: 4251-60 (1998)


Article DOI: 10.1021/jm970690q
BindingDB Entry DOI: 10.7270/Q2FB55NK
More data for this
Ligand-Target Pair