null
SMILES: NC1CCN(C1)c1c(F)cc2c3c1oc1ccc4ccccc4c1n3cc(C(O)=O)c2=O
InChI Key: InChIKey=TXLRBFMVGQVAMM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471902![]() (CHEMBL335643) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Austin Curated by ChEMBL | Assay Description Inhibition of topoisomerase II as conversion of catenated to decatenated KDNA | J Med Chem 41: 4273-8 (1998) Article DOI: 10.1021/jm980265c BindingDB Entry DOI: 10.7270/Q25X2CPR | |||||||||||
More data for this Ligand-Target Pair |