BindingDB logo
myBDB logout

null

SMILES: N[C@H]1CCN(C1)c1c(F)cc2c3c1oc1ccc4ccccc4c1n3cc(C(O)=O)c2=O

InChI Key: InChIKey=TXLRBFMVGQVAMM-ZDUSSCGKSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50471903   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha/2-beta


(Homo sapiens (Human))		BDBM50471903
PNG
(CHEMBL335387)
Show SMILES N[C@H]1CCN(C1)c1c(F)cc2c3c1oc1ccc4ccccc4c1n3cc(C(O)=O)c2=O
Show InChI InChI=1S/C24H18FN3O4/c25-17-9-15-20-23(21(17)27-8-7-13(26)10-27)32-18-6-5-12-3-1-2-4-14(12)19(18)28(20)11-16(22(15)29)24(30)31/h1-6,9,11,13H,7-8,10,26H2,(H,30,31)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 720n/an/an/an/an/an/a



The University of Texas at Austin

Curated by ChEMBL


Assay Description
Inhibition of topoisomerase II as conversion of catenated to decatenated KDNA

J Med Chem 41: 4273-8 (1998)


Article DOI: 10.1021/jm980265c
BindingDB Entry DOI: 10.7270/Q25X2CPR
More data for this
Ligand-Target Pair