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SMILES: Cc1ncsc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1

InChI Key: InChIKey=RLEAWABYZLHNEG-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50471997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471997 (CHEMBL343459) Show SMILES Cc1ncsc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C28H26N2O4S/c1-19-26(35-18-29-19)15-16-34-22-13-11-20(12-14-22)17-25(28(32)33)30-24-10-6-5-9-23(24)27(31)21-7-3-2-4-8-21/h2-14,18,25,30H,15-17H2,1H3,(H,32,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gamma				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471997 (CHEMBL343459) Show SMILES Cc1ncsc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C28H26N2O4S/c1-19-26(35-18-29-19)15-16-34-22-13-11-20(12-14-22)17-25(28(32)33)30-24-10-6-5-9-23(24)27(31)21-7-3-2-4-8-21/h2-14,18,25,30H,15-17H2,1H3,(H,32,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gamma				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471997 (CHEMBL343459) Show SMILES Cc1ncsc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C28H26N2O4S/c1-19-26(35-18-29-19)15-16-34-22-13-11-20(12-14-22)17-25(28(32)33)30-24-10-6-5-9-23(24)27(31)21-7-3-2-4-8-21/h2-14,18,25,30H,15-17H2,1H3,(H,32,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	324	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471997 (CHEMBL343459) Show SMILES Cc1ncsc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C28H26N2O4S/c1-19-26(35-18-29-19)15-16-34-22-13-11-20(12-14-22)17-25(28(32)33)30-24-10-6-5-9-23(24)27(31)21-7-3-2-4-8-21/h2-14,18,25,30H,15-17H2,1H3,(H,32,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	759	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Ability to promote differentiation of C3H10T1/2 stem cells to adipocytes using lipogenesis assay mediated through activation of Peroxisome proliferat...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
					More data for this Ligand-Target Pair