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SMILES: CN(C)c1ccc(CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(O)=O)cc2)cc1

InChI Key: InChIKey=VNLOLGBBFUHTBM-PMERELPUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472008   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50472008
PNG
(CHEMBL146029)
Show SMILES CN(C)c1ccc(CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(O)=O)cc2)cc1
Show InChI InChI=1S/C32H32N2O4/c1-34(2)26-16-12-23(13-17-26)20-21-38-27-18-14-24(15-19-27)22-30(32(36)37)33-29-11-7-6-10-28(29)31(35)25-8-4-3-5-9-25/h3-19,30,33H,20-22H2,1-2H3,(H,36,37)/t30-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 117n/an/an/an/an/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gamma

J Med Chem 41: 5037-54 (1998)


Article DOI: 10.1021/jm980413z
BindingDB Entry DOI: 10.7270/Q2J38W9F
More data for this
Ligand-Target Pair