BDBM50472755 CHEMBL111453

SMILES: Fc1ccc2c(noc2c1)C1CCN(CCC2CC3=CC=CC3C2=O)CC1

InChI Key: InChIKey=GGEFSRKFXAJIQL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50472755 (CHEMBL111453) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCC2CC3=CC=CC3C2=O)CC1 |c:22,t:20| Show InChI InChI=1S/C22H23FN2O2/c23-17-4-5-19-20(13-17)27-24-21(19)14-6-9-25(10-7-14)11-8-16-12-15-2-1-3-18(15)22(16)26/h1-5,13-14,16,18H,6-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Kinetic inhibition constant evaluated by measuring serotonergic activity				J Med Chem 43: 3233-43 (2000) Article DOI: 10.1021/jm000941m BindingDB Entry DOI: 10.7270/Q2QJ7M2N
					More data for this Ligand-Target Pair