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SMILES: COC(=O)CC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C

InChI Key: InChIKey=AEJZQZKFMMDIMX-VUROTCPHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472981   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50472981
PNG
(CHEMBL133697)
Show SMILES COC(=O)CC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C |TLB:13:12:19:8.9,THB:5:6:19:8.9|
Show InChI InChI=1S/C18H25NO2/c1-19-14-8-10-17(19)15(9-11-18(20)21-2)16(12-14)13-6-4-3-5-7-13/h3-7,14-17H,8-12H2,1-2H3/t14?,15-,16+,17?/m0/s1
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 23n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand

J Med Chem 43: 4151-9 (2000)


Article DOI: 10.1021/jm990472s
BindingDB Entry DOI: 10.7270/Q2PK0JWZ
More data for this
Ligand-Target Pair