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SMILES: COC(=O)\C=C\CC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C

InChI Key: InChIKey=KKDYFWAMQQRXLV-ZUMPLFDISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472991   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50472991
PNG
(CHEMBL132730)
Show SMILES COC(=O)\C=C\CC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C |TLB:15:14:21:10.11,THB:7:8:21:10.11|
Show InChI InChI=1S/C20H27NO2/c1-21-16-12-13-19(21)17(10-6-7-11-20(22)23-2)18(14-16)15-8-4-3-5-9-15/h3-5,7-9,11,16-19H,6,10,12-14H2,1-2H3/b11-7+/t16?,17-,18+,19?/m0/s1
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 20n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand

J Med Chem 43: 4151-9 (2000)


Article DOI: 10.1021/jm990472s
BindingDB Entry DOI: 10.7270/Q2PK0JWZ
More data for this
Ligand-Target Pair