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SMILES: [H][C@@]12CCCC[C@]1([H])C(=NN(Cc1ccccc1)C2=O)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=SPNSPIATZGICGL-RBUKOAKNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473350   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50473350
PNG
(CHEMBL313170)
Show SMILES [H][C@@]12CCCC[C@]1([H])C(=NN(Cc1ccccc1)C2=O)c1ccc(OC)c(OC)c1 |c:9|
Show InChI InChI=1S/C23H26N2O3/c1-27-20-13-12-17(14-21(20)28-2)22-18-10-6-7-11-19(18)23(26)25(24-22)15-16-8-4-3-5-9-16/h3-5,8-9,12-14,18-19H,6-7,10-11,15H2,1-2H3/t18-,19+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.90n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibition of PDE4 in the cytosol of human neutrophils

J Med Chem 44: 2511-22 (2001)


Article DOI: 10.1021/jm010837k
BindingDB Entry DOI: 10.7270/Q27D2XWH
More data for this
Ligand-Target Pair