null

SMILES: COc1ccc(cc1OCCCCCCOc1ccc(cc1)C(O)=O)C1=NN(C2CCCCCC2)C(=O)C2CC=CCC12

InChI Key: InChIKey=OFNKSFVKBAHXFD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50473368 (CHEMBL83869) Show SMILES COc1ccc(cc1OCCCCCCOc1ccc(cc1)C(O)=O)C1=NN(C2CCCCCC2)C(=O)C2CC=CCC12 |c:42,t:27| Show InChI InChI=1S/C35H44N2O6/c1-41-31-21-18-26(24-32(31)43-23-11-5-4-10-22-42-28-19-16-25(17-20-28)35(39)40)33-29-14-8-9-15-30(29)34(38)37(36-33)27-12-6-2-3-7-13-27/h8-9,16-21,24,27,29-30H,2-7,10-15,22-23H2,1H3,(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory activity of the against phosphodiesterase 3 (PDE3); No significant inhibitory activity at pIC50				J Med Chem 44: 2523-35 (2001) Article DOI: 10.1021/jm010838c BindingDB Entry DOI: 10.7270/Q23N2644
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50473368 (CHEMBL83869) Show SMILES COc1ccc(cc1OCCCCCCOc1ccc(cc1)C(O)=O)C1=NN(C2CCCCCC2)C(=O)C2CC=CCC12 |c:42,t:27| Show InChI InChI=1S/C35H44N2O6/c1-41-31-21-18-26(24-32(31)43-23-11-5-4-10-22-42-28-19-16-25(17-20-28)35(39)40)33-29-14-8-9-15-30(29)34(38)37(36-33)27-12-6-2-3-7-13-27/h8-9,16-21,24,27,29-30H,2-7,10-15,22-23H2,1H3,(H,39,40)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 4 (PDE4) in human neutrophils				J Med Chem 44: 2523-35 (2001) Article DOI: 10.1021/jm010838c BindingDB Entry DOI: 10.7270/Q23N2644
					More data for this Ligand-Target Pair