BDBM50473550 CHEMBL354072

SMILES: Cc1cccc2CCC(CC3CN=CN3)=Cc12

InChI Key: InChIKey=RCVCPNOVWAAUOC-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50473550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50473550 (CHEMBL354072) Show SMILES Cc1cccc2CCC(CC3CN=CN3)=Cc12 |c:12,15| Show InChI InChI=1S/C15H18N2/c1-11-3-2-4-13-6-5-12(8-15(11)13)7-14-9-16-10-17-14/h2-4,8,10,14H,5-7,9H2,1H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity was determined against serotonin reuptake site of rat in presence of [3H]paroxetine radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473550 (CHEMBL354072) Show SMILES Cc1cccc2CCC(CC3CN=CN3)=Cc12 |c:12,15| Show InChI InChI=1S/C15H18N2/c1-11-3-2-4-13-6-5-12(8-15(11)13)7-14-9-16-10-17-14/h2-4,8,10,14H,5-7,9H2,1H3,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity against alpha-2 adrenergic receptor of rat in presence of [3H]-RX 821002 radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473550 (CHEMBL354072) Show SMILES Cc1cccc2CCC(CC3CN=CN3)=Cc12 |c:12,15| Show InChI InChI=1S/C15H18N2/c1-11-3-2-4-13-6-5-12(8-15(11)13)7-14-9-16-10-17-14/h2-4,8,10,14H,5-7,9H2,1H3,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity against alpha-1 adrenergic receptor of rat in presence of [3H]-prazosin radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus)	BDBM50473550 (CHEMBL354072) Show SMILES Cc1cccc2CCC(CC3CN=CN3)=Cc12 |c:12,15| Show InChI InChI=1S/C15H18N2/c1-11-3-2-4-13-6-5-12(8-15(11)13)7-14-9-16-10-17-14/h2-4,8,10,14H,5-7,9H2,1H3,(H,16,17)	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity was determined against NA (noradrenaline) reuptake site of rat in presence of [3H]nisoxetine radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair