BDBM50473565 CHEMBL436234

SMILES: Fc1ccc2CCC(CC3CN=CN3)=Cc2c1

InChI Key: InChIKey=WWUPWXOAAVDTKR-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50473565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50473565 (CHEMBL436234) Show SMILES Fc1ccc2CCC(CC3CN=CN3)=Cc2c1 |c:11,14| Show InChI InChI=1S/C14H15FN2/c15-13-4-3-11-2-1-10(5-12(11)7-13)6-14-8-16-9-17-14/h3-5,7,9,14H,1-2,6,8H2,(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity was determined against serotonin reuptake site of rat in presence of [3H]paroxetine radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus)	BDBM50473565 (CHEMBL436234) Show SMILES Fc1ccc2CCC(CC3CN=CN3)=Cc2c1 |c:11,14| Show InChI InChI=1S/C14H15FN2/c15-13-4-3-11-2-1-10(5-12(11)7-13)6-14-8-16-9-17-14/h3-5,7,9,14H,1-2,6,8H2,(H,16,17)	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity was determined against NA (noradrenaline) reuptake site of rat in presence of [3H]nisoxetine radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473565 (CHEMBL436234) Show SMILES Fc1ccc2CCC(CC3CN=CN3)=Cc2c1 |c:11,14| Show InChI InChI=1S/C14H15FN2/c15-13-4-3-11-2-1-10(5-12(11)7-13)6-14-8-16-9-17-14/h3-5,7,9,14H,1-2,6,8H2,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description Binding affinity for human alpha-2 adrenergic receptor expressed in CHO cell				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473565 (CHEMBL436234) Show SMILES Fc1ccc2CCC(CC3CN=CN3)=Cc2c1 |c:11,14| Show InChI InChI=1S/C14H15FN2/c15-13-4-3-11-2-1-10(5-12(11)7-13)6-14-8-16-9-17-14/h3-5,7,9,14H,1-2,6,8H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity against alpha-2 adrenergic receptor of rat in presence of [3H]-RX 821002 radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473565 (CHEMBL436234) Show SMILES Fc1ccc2CCC(CC3CN=CN3)=Cc2c1 |c:11,14| Show InChI InChI=1S/C14H15FN2/c15-13-4-3-11-2-1-10(5-12(11)7-13)6-14-8-16-9-17-14/h3-5,7,9,14H,1-2,6,8H2,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database					Assay Description In vitro binding affinity against alpha-1 adrenergic receptor of rat in presence of [3H]-prazosin radioligand				J Med Chem 44: 787-805 (2001) Article DOI: 10.1021/jm001040g BindingDB Entry DOI: 10.7270/Q2JQ13R9
					More data for this Ligand-Target Pair