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SMILES: O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(CC1)c1cccc2CCOc12

InChI Key: InChIKey=SXTSCSDLHDMAOP-NHCUHLMSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50473598 (CHEMBL48713) Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(CC1)c1cccc2CCOc12 Show InChI InChI=1S/C22H24FNO2/c23-17-4-5-18-16(12-17)13-20(21(18)25)24-9-6-14(7-10-24)19-3-1-2-15-8-11-26-22(15)19/h1-5,12,14,20-21,25H,6-11,13H2/t20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line				J Med Chem 45: 165-76 (2002) Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473598 (CHEMBL48713) Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(CC1)c1cccc2CCOc12 Show InChI InChI=1S/C22H24FNO2/c23-17-4-5-18-16(12-17)13-20(21(18)25)24-9-6-14(7-10-24)19-3-1-2-15-8-11-26-22(15)19/h1-5,12,14,20-21,25H,6-11,13H2/t20-,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Binding affinity at Alpha-1 adrenergic receptor by inhibition of [3H]-prazosin binding to rat cortex				J Med Chem 45: 165-76 (2002) Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9
					More data for this Ligand-Target Pair