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SMILES: O[C@H]1[C@@H](Cc2ccc(F)cc12)N1CCC(CC1)c1cccc2OCCOc12

InChI Key: InChIKey=HNIFACCWWKONLS-TZIWHRDSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50473601 (CHEMBL47433) Show SMILES O[C@H]1[C@@H](Cc2ccc(F)cc12)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H24FNO3/c23-16-5-4-15-12-19(21(25)18(15)13-16)24-8-6-14(7-9-24)17-2-1-3-20-22(17)27-11-10-26-20/h1-5,13-14,19,21,25H,6-12H2/t19-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.776	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line				J Med Chem 45: 165-76 (2002) Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473601 (CHEMBL47433) Show SMILES O[C@H]1[C@@H](Cc2ccc(F)cc12)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H24FNO3/c23-16-5-4-15-12-19(21(25)18(15)13-16)24-8-6-14(7-9-24)17-2-1-3-20-22(17)27-11-10-26-20/h1-5,13-14,19,21,25H,6-12H2/t19-,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Binding affinity at Alpha-1 adrenergic receptor by inhibition of [3H]-prazosin binding to rat cortex				J Med Chem 45: 165-76 (2002) Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9
					More data for this Ligand-Target Pair