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SMILES: COc1ccc(cc1OC)C1=NN(C2Cc3ccccc3C2)C(=O)C2CC=CCC12

InChI Key: InChIKey=CGAFBDBSTQEQKJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473690   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50473690
PNG
(CHEMBL85093)
Show SMILES COc1ccc(cc1OC)C1=NN(C2Cc3ccccc3C2)C(=O)C2CC=CCC12 |c:29,t:11|
Show InChI InChI=1S/C25H26N2O3/c1-29-22-12-11-18(15-23(22)30-2)24-20-9-5-6-10-21(20)25(28)27(26-24)19-13-16-7-3-4-8-17(16)14-19/h3-8,11-12,15,19-21H,9-10,13-14H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.794n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils

J Med Chem 45: 2520-5 (2002)


Article DOI: 10.1021/jm0110340
BindingDB Entry DOI: 10.7270/Q2862K56
More data for this
Ligand-Target Pair