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SMILES: COc1ccc(cc1OC)C1=NN(Cc2ccc(cc2)C(O)=O)C(=O)C2CCCCC12

InChI Key: InChIKey=PVWGPCPZYAEPPN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473709   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50473709
PNG
(CHEMBL82695)
Show SMILES COc1ccc(cc1OC)C1=NN(Cc2ccc(cc2)C(O)=O)C(=O)C2CCCCC12 |t:11|
Show InChI InChI=1S/C24H26N2O5/c1-30-20-12-11-17(13-21(20)31-2)22-18-5-3-4-6-19(18)23(27)26(25-22)14-15-7-9-16(10-8-15)24(28)29/h7-13,18-19H,3-6,14H2,1-2H3,(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils

J Med Chem 45: 2520-5 (2002)


Article DOI: 10.1021/jm0110340
BindingDB Entry DOI: 10.7270/Q2862K56
More data for this
Ligand-Target Pair