BDBM50474297 CHEMBL115002

SMILES: Clc1cc(Cl)cc(\[#6]=[#6]-2/c3ccccc3-[#6](=O)-c3ccccc-23)c1

InChI Key: InChIKey=VRPYPFAIAPTTDN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50474297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50474297 (CHEMBL115002) Show SMILES Clc1cc(Cl)cc(\[#6]=[#6]-2/c3ccccc3-[#6](=O)-c3ccccc-23)c1 Show InChI InChI=1S/C21H12Cl2O/c22-14-9-13(10-15(23)12-14)11-20-16-5-1-3-7-18(16)21(24)19-8-4-2-6-17(19)20/h1-12H	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Westphalian Wilhelms-University Curated by ChEMBL					Assay Description In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees C				J Med Chem 46: 3382-94 (2003) Article DOI: 10.1021/jm0307685 BindingDB Entry DOI: 10.7270/Q2VT1VVK
					More data for this Ligand-Target Pair