BindingDB logo
myBDB logout

null

SMILES: Clc1ncc(OC[C@@H]2CCN2)cc1-c1ccc(Br)nc1

InChI Key: InChIKey=GCESCLVBELOUPK-JTQLQIEISA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50474583   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))		BDBM50474583
PNG
(CHEMBL86051)
Show SMILES Clc1ncc(OC[C@@H]2CCN2)cc1-c1ccc(Br)nc1
Show InChI InChI=1S/C14H13BrClN3O/c15-13-2-1-9(6-18-13)12-5-11(7-19-14(12)16)20-8-10-3-4-17-10/h1-2,5-7,10,17H,3-4,8H2/t10-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 0.00430n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature

J Med Chem 47: 2453-65 (2004)


Article DOI: 10.1021/jm030432v
BindingDB Entry DOI: 10.7270/Q21C20MJ
More data for this
Ligand-Target Pair