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SMILES: [O-][N+](=O)c1cc(ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=IZGNCBBIDDSQGU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50475110   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))		BDBM50475110
PNG
(CHEMBL186707)
Show SMILES [O-][N+](=O)c1cc(ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C14H8ClF3N2O5S/c15-9-2-4-10(5-3-9)26(24,25)19-13(21)11-6-1-8(14(16,17)18)7-12(11)20(22)23/h1-7H,(H,19,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation

J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair