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SMILES: COc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=BKGLNEFMULBVPX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50475112   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475112
PNG
(CHEMBL363071)
Show SMILES COc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-13-8-10(16)4-7-12(13)14(18)17-22(19,20)11-5-2-9(15)3-6-11/h2-8H,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair