BDBM50475113 CHEMBL365275
SMILES: Clc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI Key: InChIKey=IZIJDUMIQKCMGD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human)) | BDBM50475113 (CHEMBL365275) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation | J Med Chem 47: 5367-80 (2004) Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 | |||||||||||
More data for this Ligand-Target Pair |