BDBM50475140 CHEMBL426981

SMILES: COc1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=QYUOZIXOUFDURP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50475140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor (Homo sapiens (Human))	BDBM50475140 (CHEMBL426981) Show SMILES COc1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-10-3-2-4-11(8-10)22(19,20)17-14(18)12-6-5-9(15)7-13(12)16/h2-8H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 47: 5367-80 (2004) Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8
					More data for this Ligand-Target Pair