BDBM50475154 CHEMBL187967
SMILES: Clc1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
InChI Key: InChIKey=WNZYDSHFADUYSA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor (Homo sapiens (Human)) | BDBM50475154 (CHEMBL187967) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation | J Med Chem 47: 5367-80 (2004) Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 | |||||||||||
More data for this Ligand-Target Pair |