BDBM50475541 CHEMBL196754

SMILES: COc1ccc2\C(=C/c3ccc(O)cc3)C(=O)Nc2c1

InChI Key: InChIKey=PBLOJPUYFVSJDO-RIYZIHGNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50475541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50475541 (CHEMBL196754) Show SMILES COc1ccc2\C(=C/c3ccc(O)cc3)C(=O)Nc2c1 Show InChI InChI=1S/C16H13NO3/c1-20-12-6-7-13-14(16(19)17-15(13)9-12)8-10-2-4-11(18)5-3-10/h2-9,18H,1H3,(H,17,19)/b14-8+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization by GTP-induced assembly				Bioorg Med Chem Lett 15: 5382-5 (2005) Article DOI: 10.1016/j.bmcl.2005.09.001 BindingDB Entry DOI: 10.7270/Q2Z322D9
					More data for this Ligand-Target Pair