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SMILES: Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O

InChI Key: InChIKey=SYZZNDUHVRATSW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50475811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha-4-beta-2 nACHR expressed in human HEK293 cells				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha-2-beta-2 nACHR expressed in human HEK293 cells				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat forebrain alpha4beta2 nACHR				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha-4-beta-4 nACHR expressed in human HEK293 cells				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-4 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha-2-beta-4 nACHR expressed in human HEK293 cells				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha-3-beta-2 nACHR expressed in human HEK293 cells				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rattus norvegicus (Rat))	BDBM50475811 (CHEMBL382845) Show SMILES Fc1ccc(cc1)-c1ccc2C3CNCC(C3)Cn2c1=O Show InChI InChI=1S/C17H17FN2O/c18-14-3-1-12(2-4-14)15-5-6-16-13-7-11(8-19-9-13)10-20(16)17(15)21/h1-6,11,13,19H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha3beta4 nACHR expressed in human HEK293 cells				J Med Chem 49: 2673-6 (2006) Article DOI: 10.1021/jm051196m BindingDB Entry DOI: 10.7270/Q2GX4F96
					More data for this Ligand-Target Pair