BDBM50477185 CHEMBL239338

SMILES: CC(C)N(C)c1nc(C(C)c2c(F)cccc2F)c(C)c(=O)[nH]1

InChI Key: InChIKey=VQJKUVSKZOTZTB-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50477185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50477185 (CHEMBL239338) Show SMILES CC(C)N(C)c1nc(C(C)c2c(F)cccc2F)c(C)c(=O)[nH]1 Show InChI InChI=1S/C17H21F2N3O/c1-9(2)22(5)17-20-15(11(4)16(23)21-17)10(3)14-12(18)7-6-8-13(14)19/h6-10H,1-5H3,(H,20,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase V106A mutant				J Med Chem 50: 5412-24 (2007) Article DOI: 10.1021/jm070811e BindingDB Entry DOI: 10.7270/Q2H99803
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50477185 (CHEMBL239338) Show SMILES CC(C)N(C)c1nc(C(C)c2c(F)cccc2F)c(C)c(=O)[nH]1 Show InChI InChI=1S/C17H21F2N3O/c1-9(2)22(5)17-20-15(11(4)16(23)21-17)10(3)14-12(18)7-6-8-13(14)19/h6-10H,1-5H3,(H,20,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 3B reverse transcriptase				J Med Chem 50: 5412-24 (2007) Article DOI: 10.1021/jm070811e BindingDB Entry DOI: 10.7270/Q2H99803
					More data for this Ligand-Target Pair
Reverse Transcriptase (Human immunodeficiency virus 1)	BDBM50477185 (CHEMBL239338) Show SMILES CC(C)N(C)c1nc(C(C)c2c(F)cccc2F)c(C)c(=O)[nH]1 Show InChI InChI=1S/C17H21F2N3O/c1-9(2)22(5)17-20-15(11(4)16(23)21-17)10(3)14-12(18)7-6-8-13(14)19/h6-10H,1-5H3,(H,20,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant				J Med Chem 50: 5412-24 (2007) Article DOI: 10.1021/jm070811e BindingDB Entry DOI: 10.7270/Q2H99803
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50477185 (CHEMBL239338) Show SMILES CC(C)N(C)c1nc(C(C)c2c(F)cccc2F)c(C)c(=O)[nH]1 Show InChI InChI=1S/C17H21F2N3O/c1-9(2)22(5)17-20-15(11(4)16(23)21-17)10(3)14-12(18)7-6-8-13(14)19/h6-10H,1-5H3,(H,20,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188L mutant				J Med Chem 50: 5412-24 (2007) Article DOI: 10.1021/jm070811e BindingDB Entry DOI: 10.7270/Q2H99803
					More data for this Ligand-Target Pair
Reverse Transcriptase (Human immunodeficiency virus 1)	BDBM50477185 (CHEMBL239338) Show SMILES CC(C)N(C)c1nc(C(C)c2c(F)cccc2F)c(C)c(=O)[nH]1 Show InChI InChI=1S/C17H21F2N3O/c1-9(2)22(5)17-20-15(11(4)16(23)21-17)10(3)14-12(18)7-6-8-13(14)19/h6-10H,1-5H3,(H,20,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase L100I mutant				J Med Chem 50: 5412-24 (2007) Article DOI: 10.1021/jm070811e BindingDB Entry DOI: 10.7270/Q2H99803
					More data for this Ligand-Target Pair