Found 4 hits for monomerid = 50477406 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50477406
![PNG](/data/jpeg/tenK5047/BindingDB_50477406.png) (CHEMBL241500)Show SMILES Cc1ccc2c(OCCN3CCC(Cc4ccc5OCC(=O)Nc5c4)CC3)ccc(Cl)c2n1 Show InChI InChI=1S/C26H28ClN3O3/c1-17-2-4-20-23(7-5-21(27)26(20)28-17)32-13-12-30-10-8-18(9-11-30)14-19-3-6-24-22(15-19)29-25(31)16-33-24/h2-7,15,18H,8-14,16H2,1H3,(H,29,31) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of [3H]5-HT uptake at SERT in rat cortical synaptosomes |
Bioorg Med Chem Lett 17: 1033-6 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.031 BindingDB Entry DOI: 10.7270/Q2348P5G |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50477406
![PNG](/data/jpeg/tenK5047/BindingDB_50477406.png) (CHEMBL241500)Show SMILES Cc1ccc2c(OCCN3CCC(Cc4ccc5OCC(=O)Nc5c4)CC3)ccc(Cl)c2n1 Show InChI InChI=1S/C26H28ClN3O3/c1-17-2-4-20-23(7-5-21(27)26(20)28-17)32-13-12-30-10-8-18(9-11-30)14-19-3-6-24-22(15-19)29-25(31)16-33-24/h2-7,15,18H,8-14,16H2,1H3,(H,29,31) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 1033-6 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.031 BindingDB Entry DOI: 10.7270/Q2348P5G |
More data for this Ligand-Target Pair | |
Serotonin (5-HT) receptor
(Homo sapiens (Human)) | BDBM50477406
![PNG](/data/jpeg/tenK5047/BindingDB_50477406.png) (CHEMBL241500)Show SMILES Cc1ccc2c(OCCN3CCC(Cc4ccc5OCC(=O)Nc5c4)CC3)ccc(Cl)c2n1 Show InChI InChI=1S/C26H28ClN3O3/c1-17-2-4-20-23(7-5-21(27)26(20)28-17)32-13-12-30-10-8-18(9-11-30)14-19-3-6-24-22(15-19)29-25(31)16-33-24/h2-7,15,18H,8-14,16H2,1H3,(H,29,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 1033-6 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.031 BindingDB Entry DOI: 10.7270/Q2348P5G |
More data for this Ligand-Target Pair | |
Serotonin (5-HT) receptor
(Homo sapiens (Human)) | BDBM50477406
![PNG](/data/jpeg/tenK5047/BindingDB_50477406.png) (CHEMBL241500)Show SMILES Cc1ccc2c(OCCN3CCC(Cc4ccc5OCC(=O)Nc5c4)CC3)ccc(Cl)c2n1 Show InChI InChI=1S/C26H28ClN3O3/c1-17-2-4-20-23(7-5-21(27)26(20)28-17)32-13-12-30-10-8-18(9-11-30)14-19-3-6-24-22(15-19)29-25(31)16-33-24/h2-7,15,18H,8-14,16H2,1H3,(H,29,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from human cloned 5HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 1033-6 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.031 BindingDB Entry DOI: 10.7270/Q2348P5G |
More data for this Ligand-Target Pair | |