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SMILES: COc1cc(\C=C\c2ccc(O)c(OC)c2)nc(\C=C\c2ccc(O)c(OC)c2)c1

InChI Key: InChIKey=KWAMKCMHCVLFEH-KBXRYBNXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477445   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50477445
PNG
(CHEMBL247726)
Show SMILES COc1cc(\C=C\c2ccc(O)c(OC)c2)nc(\C=C\c2ccc(O)c(OC)c2)c1
Show InChI InChI=1S/C24H23NO5/c1-28-20-14-18(8-4-16-6-10-21(26)23(12-16)29-2)25-19(15-20)9-5-17-7-11-22(27)24(13-17)30-3/h4-15,26-27H,1-3H3/b8-4+,9-5+
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MMDB

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PC cid
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Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of amyloid beta 42 fibril formation by thioflavin T assay

Bioorg Med Chem Lett 17: 1466-70 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.090
BindingDB Entry DOI: 10.7270/Q2PV6P4S
More data for this
Ligand-Target Pair